Cheng-Yoong Pang, Ph.D.,Associate Professor


Education: Ph.D., National Yang-Ming University
Research Fields: 1. Stem Cells Biology 2. Biochemistry 3. Translational Medical Research
E-mail: cypang@mail.tcu.edu.tw
TEL:886-3-856-1825 ext.15613

Publication (recent 5 years)：

  1. Li CJ, Sun LY, Pang CY. Synergistic Protection of N-Acetylcysteine and Ascorbic Acid 2-Phosphate on Human Mesenchymal Stem cells Against Mitoptosis, Necroptosis and Apoptosis. Sci Reports, in press.
  2. Liew HK, Kuo JS, Wang JY, Pang CY. Granulocyte-Colony Stimulating Factor Increases Cerebral Blood Flow via a NO Surge Mediated by Akt/eNOS Pathway to Reduce Ischemic Injury. Scientific World J. Article ID 657932, in press.
  3. Huang HY, Chiu TL, Chang HF, Hsu HR, Pang CY, Liew HK, Wang MJ. Epigenetic Regulation Contributes to Urocortin-Enhanced Midbrain Dopaminergic Neuron Differentiation. Stem Cells. 2015 Jan 13. doi: 10.1002/stem.1949. [Epub ahead of print] PubMed PMID: 25641682.
  4. Chou CL, Pang CY, Lee TJ, Fang TC. Beneficial effects of calcitriol on hypertension, glucose intolerance, impairment of endothelium-dependent vascular relaxation, and visceral adiposity in fructose-fed hypertensive rats. PLoS One. 2015 Mar 16;10(3):e0119843. doi: 10.1371/journal.pone.0119843. eCollection 2015. PubMed PMID: 25774877.
  5. Chiu SC, Huang SY, Chang SF, Chen SP, Chen CC, Lin TH, Liu HH, Tsai TH, Lee SS, Pang CY, Hsieh TF. Potential therapeutic roles of tanshinone IIA in human bladder cancer cells. Int J Mol Sci. 2014 Sep 4;15(9):15622-37. doi: 10.3390/ijms150915622. PubMed PMID: 25192287; PubMed Central PMCID: PMC4200770.
  6. Chiu SC, Huang SY, Chen SP, Su CC, Chiu TL, Pang CY. Tanshinone IIA inhibits human prostate cancer cells growth by induction of endoplasmic reticulum stress in vitro and in vivo. Prostate Cancer Prostatic Dis. 2013 Dec;16(4):315-22. doi: 10.1038/pcan.2013.38. Epub 2013 Sep 17. PubMed PMID: 24042854.
  7. Pang CY, Chiu SC, Harn HJ, Zhai WJ, Lin SZ, Yang HH. Proteomic-based identification of multiple pathways underlying n-butylidenephthalide-induced apoptosis in LNCaP human prostate cancer cells. Food Chem Toxicol. 2013 Sep;59:281-8. doi: 10.1016/j.fct.2013.05.045. Epub 2013 Jun 12. PubMed PMID: 23770345.
  8. Liao CH, Chen SY, Kuo JS, Pang CY. Reduction of motor disorder in 6-OHDA-induced severe parkinsonism rats by post treatment with granulocyte-colony stimulating factor. Chin J Physiol. 2013 Jun 30;56(3):147-54. PubMed PMID: 23656216.
  9. Yang JR, Liao CH, Pang CY, Huang LL, Chen YL, Shiue YL, Chen LR. Transplantation of porcine embryonic stem cells and their derived neuronal progenitors in a spinal cord injury rat model. Cytotherapy. 2013 Feb;15(2):201-8. doi: 10.1016/j.jcyt.2012.09.001. Epub 2012 Dec 12. Erratum in: Cytotherapy. 2013 May;15(5):627. PubMed PMID: 23245953.
  10. Chou CL, Pang CY, Lee TJ, Fang TC. Direct renin inhibitor prevents and ameliorates insulin resistance, aortic endothelial dysfunction and vascular remodeling in fructose-fed hypertensive rats. Hypertens Res. 2013 Feb;36(2):123-8. doi: 10.1038/hr.2012.124. Epub 2012 Aug 16. PubMed PMID: 22895064.
  11. Lin HZ, Pang CY, Chen SP, Tsai RK. Vision improvement in a Taiwanese (Han Chinese) family with Leber’s hereditary optic neuropathy. Kaohsiung J Med Sci. 2012 Dec;28(12):679-82. doi: 10.1016/j.kjms.2012.04.038. Epub 2012 Jul 28. PubMed PMID: 23217361.
  12. Chen SP, Wu CC, Huang SY, Kang JC, Chiu SC, Yang KL, Pang CY. β-catenin and K-ras mutations and RASSF1A promoter methylation in Taiwanese colorectal cancer patients. Genet Test Mol Biomarkers. 2012 Nov;16(11):1277-81. doi: 10.1089/gtmb.2012.0126. Epub 2012 Sep 25. PubMed PMID: 23009572.
  13. Yang KL, Lee JT, Pang CY, Lee TY, Chen SP, Liew HK, Chen SY, Chen TY, Lin PY. Human adipose-derived stem cells for the treatment of intracerebral hemorrhage in rats via femoral intravenous injection. Cell Mol Biol Lett. 2012 Sep;17(3):376-92. doi: 10.2478/s11658-012-0016-5. Epub 2012 Apr 28. PubMed PMID: 22544763.
  14. Chiu SC, Huang SY, Tsai YC, Chen SP, Pang CY, Lien CF, Lin YJ, Yang KT. Poly (ADP-ribose) polymerase plays an important role in intermittent hypoxia-induced cell death in rat cerebellar granule cells. J Biomed Sci. 2012 Mar 9;19:29. doi: 10.1186/1423-0127-19-29. PubMed PMID: 22405498; PubMed Central PMCID: PMC3317837.
  15. Liew HK, Pang CY, Hsu CW, Wang MJ, Li TY, Peng HF, Kuo JS, Wang JY. Systemic administration of urocortin after intracerebral hemorrhage reduces neurological deficits and neuroinflammation in rats. J Neuroinflammation. 2012 Jan 19;9:13. doi: 10.1186/1742-2094-9-13. PubMed PMID: 22257737; PubMed Central PMCID: PMC3271957.
  16. Liew HK, Hsu CW, Wang MJ, Kuo JS, Li TY, Peng HF, Wang JY, Pang CY. Therapeutic benefit of urocortin in rats with intracerebral hemorrhage. J Neurosurg. 2012 Jan;116(1):193-200. doi: 10.3171/2011.8.JNS101637. Epub 2011 Oct 7. PubMed PMID: 21981644.
  17. Fang TC, Pang CY, Chiu SC, Ding DC, Tsai RK. Renoprotective effect of human umbilical cord-derived mesenchymal stem cells in immunodeficient mice suffering from acute kidney injury. PLoS One. 2012;7(9):e46504. doi: 10.1371/journal.pone.0046504. Epub 2012 Sep 27. PubMed PMID: 23029541; PubMed Central PMCID: PMC3459926.
  18. Chiu SC, Chen SP, Huang SY, Wang MJ, Lin SZ, Harn HJ, Pang CY. Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide. PLoS One. 2012;7(3):e33742. doi: 10.1371/journal.pone.0033742. Epub 2012 Mar 28. PubMed PMID: 22470469; PubMed Central PMCID: PMC3314677.
  19. Chiu SC, Wang MJ, Yang HH, Chen SP, Huang SY, Chen YL, Lin SZ, Harn HJ, Pang CY. Activation of NAG-1 via JNK signaling revealed an isochaihulactone-triggered cell death in human LNCaP prostate cancer cells. BMC Cancer. 2011 Apr 20;11:146. doi: 10.1186/1471-2407-11-146. PubMed PMID: 21504622; PubMed Central PMCID: PMC3095567.
  20. Lin BF, Ou MC, Chung SS, Pang CY, Chen HH. Adolescent toluene exposure produces enduring social and cognitive deficits in mice: an animal model of solvent-induced psychosis. World J Biol Psychiatry. 2010 Sep;11(6):792-802. doi: 10.3109/15622970903406234. PubMed PMID: 20001362.
  21. Yang JR, Liao CH, Pang CY, Huang LL, Lin YT, Chen YL, Shiue YL, Chen LR. Directed differentiation into neural lineages and therapeutic potential of porcine embryonic stem cells in rat Parkinson’s disease model. Cell Reprogram. 2010 Aug;12(4):447-61. doi: 10.1089/cell.2009.0078. PubMed PMID: 20698783.