Tsung-Cheng Hsieh, Ph.D., Professor

Education: Ph.D., Department of Agronomy, National Taiwan University
Research Fields: 1.Clinical trial design   2.Statistics in Medicine and Pharmacy
E-mail: tchsieh@mail.tcu.edu.tw , tchsieh@gms.tcu.edu.tw
TEL: 886-3-856-5301 ext.2015


Recent Publications (2017~):

  1. Hong YL, Hsieh TC, Chen PR, Chang SC. Nurse-Led Counseling Intervention of Postoperative Home-Based Exercise Training Improves Shoulder Pain, Shoulder Disability, and Quality of Life in Newly Diagnosed Head and Neck Cancer Patients. J Clin Med. 2022 Jul 12;11(14):4032. doi: 10.3390/jcm11144032. PMID: 35887795; PMCID: PMC9315873.
  2. Zhang JR, Hsieh TC, Chang FL, He MS. LAWN TRIMMER-RELATED OPEN-GLOBE INJURIES IN TAIWAN. Retina. 2022 May 1;42(5):973-980. doi: 10.1097/IAE.0000000000003402. Epub 2022 Jan 12. PMID: 35471491; PMCID: PMC9022680..
  3. Hsieh TC, Lin CC, Wu LS. Long-term use of valproic acid reduced mortality in bipolar disorder patients in a Taiwanese population: An association analysis using the national health insurance research database (NHIRD). J Psychiatr Res. 2022 May;149:339-343. doi: 10.1016/j.jpsychires.2021.11.021. Epub 2021 Nov 8. PMID: 34785038.
  4. Factors in Patients with Epidermal Growth Factor Receptor Mutations in Lung Adenocarcinoma and Treated with Tyrosine Kinase Inhibitors. J Pers Med. 2022 Mar 5;12(3):404. doi: 10.3390/jpm12030404. PMID: 35330404; PMCID: PMC8955131.
  5. Huang CH, Lue KH, Chen PR, Hsieh TC, Chou YF. Association between Sarcopenia and Immediate Complications and Mortality in Patients with Oral Cavity Squamous Cell Carcinoma Undergoing Surgery. Cancers (Basel). 2022 Feb 3;14(3):785. doi: 10.3390/cancers14030785. PMID: 35159050; PMCID: PMC8833832.
  6. Lue KH, Huang CH, Hsieh TC, Liu SH, Wu YF, Chen YH. Systemic Inflammation Index and Tumor Glycolytic Heterogeneity Help Risk Stratify Patients with Advanced Epidermal Growth Factor Receptor-Mutated Lung Adenocarcinoma Treated with Tyrosine Kinase Inhibitor Therapy. Cancers (Basel). 2022 Jan 8;14(2):309. doi: 10.3390/cancers14020309. PMID: 35053473; PMCID: PMC8773680.
  7. Shen CL, Hsieh TC, Wang TF, Huang WH, Chu SC, Wu YF. Designing a Scoring System for Differential Diagnosis From Reactive Thrombocytosis and Essential Thrombocytosis. Front Med (Lausanne). 2021 Dec 16;8:736150. doi: 10.3389/fmed.2021.736150. PMID: 34977055; PMCID: PMC8716506.
  8. Huang CH, Chen PR, Lue KH, Hsieh TC, Chou YF. Evaluation of Sarcopenia, Frailty, and Inflammation on Adverse Events and Survival Outcomes in Patients with Oral Cavity Squamous Cell Carcinoma under Adjuvant Chemoradiotherapy. J Pers Med. 2021 Sep 19;11(9):936. doi: 10.3390/jpm11090936. PMID: 34575713; PMCID: PMC8464994.
  9. Chung HC, Chen YC, Chang SC, Hsu WL, Hsieh TC. Development and Validation of Nurses’ Well-Being and Caring Nurse-Patient Interaction Model: A Psychometric Study. Int J Environ Res Public Health. 2021 Jul 21;18(15):7750. doi: 10.3390/ijerph18157750. PMID: 34360044; PMCID: PMC8345567.
  10. Pairojana T, Phasuk S, Suresh P, Huang SP, Pakaprot N, Chompoopong S, Hsieh TC, Liu IY. Age and gender differences for the behavioral phenotypes of 3xTg alzheimer’s disease mice. Brain Res. 2021 Jul 1;1762:147437. doi: 10.1016/j.brainres.2021.147437. Epub 2021 Mar 19. PMID: 33753066.
  11. Huang HJ, Lee CW, Li TH, Hsieh TC. Different Patterns in Ranking of Risk Factors for the Onset Age of Acute Myocardial Infarction between Urban and Rural Areas in Eastern Taiwan. Int J Environ Res Public Health. 2021 May 22;18(11):5558. doi: 10.3390/ijerph18115558. PMID: 34067428; PMCID: PMC8197001.
  12. Tai CH, Hsieh TC, Lee RP, Lo SF. Prevalence and Medical Resource of Patients with Diabetic Foot Ulcer: A Nationwide Population-Based Retrospective Cohort Study for 2001-2015 in Taiwan. Int J Environ Res Public Health. 2021 Feb 16;18(4):1891. doi: 10.3390/ijerph18041891. PMID: 33669255; PMCID: PMC7920020.
  13. Tai CH, Hsieh TC, Lee RP. The Effect of Two Bed Bath Practices in Cost and Vital Signs of Critically Ill Patients. Int J Environ Res Public Health. 2021 Jan 19;18(2):816. doi: 10.3390/ijerph18020816. PMID: 33477909; PMCID: PMC7833440.
  14. Lue KH, Wu YF, Lin HH, Hsieh TC, Liu SH, Chan SC, Chen YH. Prognostic Value of Baseline Radiomic Features of 18F-FDG PET in Patients with Diffuse Large B-Cell Lymphoma. Diagnostics (Basel). 2020 Dec 28;11(1):36. doi: 10.3390/diagnostics11010036. PMID: 33379166; PMCID: PMC7824203..
  15. Huang SY, Koo M, Hsieh TC, Lee RP, Sung HC. Effect of Bright Light Therapy on Depressive Symptoms in Middle-Aged and Older Patients Receiving Long-Term Hemodialysis. Int J Environ Res Public Health. 2020 Oct 23;17(21):7763. doi: 10.3390/ijerph17217763. PMID: 33114131; PMCID: PMC7660326.
  16. Wang YC, Juan SH, Chou CL, Hsieh TC, Wu JL, Fang TC. Long-Term Effects of Ketoanalogues on Mortality and Renal Outcomes in Advanced Chronic Kidney Disease Patients Receiving a Low-Protein Diet. Nutrients. 2020 Sep 4;12(9):2708. doi: 10.3390/nu12092708. PMID: 32899821; PMCID: PMC7551296.
  17. Shih CY, Chu ML, Hsieh TC, Chen HL, Lee CW. Acute Myocardial Infarction among Young Adult Men in a Region with Warm Climate: Clinical Characteristics and Seasonal Distribution. Int J Environ Res Public Health. 2020 Aug 24;17(17):6140. doi: 10.3390/ijerph17176140. PMID: 32847005; PMCID: PMC7503405.
  18. Lin HZ, Hsieh TC, Wu JL, He MS, Lee YC. Systemic Alpha1-Adrenoceptor Antagonists and Increased Risk of Open-Angle Glaucoma: A Nationwide Population-Based Cohort Study. Invest Ophthalmol Vis Sci. 2020 Aug 3;61(10):15. doi: 10.1167/iovs.61.10.15. PMID: 32766746; PMCID: PMC7441300..
  19. Lue KH, Wu YF, Liu SH, Hsieh TC, Chuang KS, Lin HH, Chen YH. Intratumor Heterogeneity Assessed by 18F-FDG PET/CT Predicts Treatment Response and Survival Outcomes in Patients with Hodgkin Lymphoma. Acad Radiol. 2020 Aug;27(8):e183-e192. doi: 10.1016/j.acra.2019.10.015. Epub 2019 Nov 21. PMID: 31761665.
  20. Chung HC, Chen YC, Chang SC, Hsu WL, Hsieh TC. Nurses’ Well-Being, Health-Promoting Lifestyle and Work Environment Satisfaction Correlation: A Psychometric Study for Development of Nursing Health and Job Satisfaction Model and Scale. Int J Environ Res Public Health. 2020 May 20;17(10):3582. doi: 10.3390/ijerph17103582. PMID: 32443758; PMCID: PMC7277543.
  21. Huang CH, Lue KH, Hsieh TC, Liu SH, Wang TF, Peng TC. Association Between Sarcopenia and Clinical Outcomes in Patients With Esophageal Cancer Under Neoadjuvant Therapy. Anticancer Res. 2020 Feb;40(2):1175-1181. doi: 10.21873/anticanres.14060. PMID: 32014971.
  22. Pan MY, Hsieh TC, Chen PH, Chen MY. Factors Associated with Tooth Loss in Postmenopausal Women: A Community-Based Cross-Sectional Study. Int J Environ Res Public Health. 2019 Oct 16;16(20):3945. doi: 10.3390/ijerph16203945. PMID: 31623275; PMCID: PMC6843320.
  23. Lue KH, Wu YF, Liu SH, Hsieh TC, Chuang KS, Lin HH, Chen YH. Prognostic Value of Pretreatment Radiomic Features of 18F-FDG PET in Patients With Hodgkin Lymphoma. Clin Nucl Med. 2019 Oct;44(10):e559-e565. doi: 10.1097/RLU.0000000000002732. PMID: 31306204.
  24. Chu ML, Shih CY, Hsieh TC, Chen HL, Lee CW, Hsieh JC. Acute Myocardial Infarction Hospitalizations between Cold and Hot Seasons in an Island across Tropical and Subtropical Climate Zones-A Population-Based Study. Int J Environ Res Public Health. 2019 Aug 2;16(15):2769. doi: 10.3390/ijerph16152769. PMID: 31382497; PMCID: PMC6696291.
  25. Chang YW, Hsieh TC, Tzeng IS, Chiu V, Huang PJ, Horng YS. Ratio and difference of the cross-sectional area of median nerve to ulnar nerve in diagnosing carpal tunnel syndrome: a case control study. BMC Med Imaging. 2019 Jul 4;19(1):52. doi: 10.1186/s12880-019-0351-3. PMID: 31272405; PMCID: PMC6610846.
  26. Chung HC, Wang LS, Wu JL, Hsieh TC. Utilization of a central venous catheter insertion care bundle in Taiwan: A cross-sectional analysis of the National Health Insurance Research Database. Ci Ji Yi Xue Za Zhi. 2019 Jul-Sep;31(3):182-187. doi: 10.4103/tcmj.tcmj_63_18. PMID: 31258295; PMCID: PMC6559030.
  27. Chen ML, Wu JL, Chen MY, Hsieh TC. Long-Term Clinical Outcome of Drug-Eluting vs. Bare-Metal Stent Implantation After Percutaneous Coronary Intervention in End-Stage Renal Disease Patients on Hemodialysis - Nationwide Cohort Study in Taiwan. Circ J. 2019 May 24;83(6):1239-1246. doi: 10.1253/circj.CJ-18-1304. Epub 2019 Apr 23. PMID: 31019157.
  28. Tseng CF, Lee SH, Hsieh TC, Lee RP. Smart Restored by Learning Exercise Alleviates the Deterioration of Cognitive Function in Older Adults with Dementia-A Quasi-Experimental Research. Int J Environ Res Public Health. 2019 Apr 9;16(7):1270. doi: 10.3390/ijerph16071270. PMID: 30970666; PMCID: PMC6480400.
  29. Huang CH, Hsieh TC, Chang BS, Wang TF, Wu JL, Chang PC, Peng TC. Enteral Access Potentially Endangers Esophageal Carcinoma Patients Under Multi-modality Therapy: A Population-based Study. Anticancer Res. 2019 Apr;39(4):2227-2232. doi: 10.21873/anticanres.13338. PMID: 30952771.
  30. Lei WY, Chang WC, Wen SH, Wong MW, Hung JS, Yi CH, Liu TT, Hsu CS, Orr WC, Vaezi MF, Pace F, Hsieh TC, Chen CL. Impact of concomitant dyspepsia and irritable bowel syndrome on symptom burden in patients with gastroesophageal reflux disease. J Formos Med Assoc. 2019 Apr;118(4):797-806. doi: 10.1016/j.jfma.2018.12.002. Epub 2018 Dec 21. PMID: 30584006.
  31. Lee TY, Hsieh TC, Sung HC, Chen WL. Internet-Delivered Cognitive Behavior Therapy for Young Taiwanese Female Nursing Students with Irritable Bowel Syndrome-A Cluster Randomized Controlled Trial. Int J Environ Res Public Health. 2019 Feb 27;16(5):708. doi: 10.3390/ijerph16050708. PMID: 30818837; PMCID: PMC6427663.
  32. Lu SY, Chen JJ, Pan JI, Fu ZX, Wu JL, Hsieh TC. The Association Between Different Patterns of Traditional Chinese Medicine Treatment and All-Cause Mortality Among Cancer Patients. Integr Cancer Ther. 2019 Jan-Dec;18:1534735418823273. doi: 10.1177/1534735418823273. PMID: 30791738; PMCID: PMC6416747.
  33. Lei WY, Chang WC, Wong MW, Hung JS, Wen SH, Yi CH, Liu TT, Chen JH, Hsu CS, Hsieh TC, Chen CL. Sleep Disturbance and Its Association with Gastrointestinal Symptoms/Diseases and Psychological Comorbidity. Digestion. 2019;99(3):205-212. doi: 10.1159/000490941. Epub 2018 Sep 4. PMID: 30179863.
  34. Huang CH, Wang TF, Wu YF, Cheng YT, Lo SF, Hsieh TC, Peng TC. Efficacy of Enteral Access in Patients with Esophageal Squamous Cell Carcinoma Under Neoadjuvant Therapy. Anticancer Res. 2018 Dec;38(12):6939-6945. doi: 10.21873/anticanres.13072. PMID: 30504413.
  35. Chou CL, Hsieh TC, Chen JS, Fang TC. Sudden Sensorineural Hearing Loss in Hemodialysis Patients Could be a Marker of Pathogenic Progression in the Mortality and Atherosclerotic Events: A National Cohort Study. Otol Neurotol. 2018 Dec;39(10):1241-1249. doi: 10.1097/MAO.0000000000001967. PMID: 30212427.
  36. He MS, Chang FL, Lin HZ, Wu JL, Hsieh TC, Lee YC. The Association Between Diabetes and Age-Related Macular Degeneration Among the Elderly in Taiwan. Diabetes Care. 2018 Oct;41(10):2202-2211. doi: 10.2337/dc18-0707. Epub 2018 Jul 30. PMID: 30061321.
  37. Chung HC, Hsieh TC, Chen YC, Chang SC, Hsu WL. Cross-cultural adaptation and validation of the Chinese Comfort, Afford, Respect, and Expect scale of caring nurse-patient interaction competence. J Clin Nurs. 2018 Sep;27(17-18):3287-3297. doi: 10.1111/jocn.14196. Epub 2018 Jan 11. PMID: 29193453.
  38. Lin CC, Hsieh TC, Wu LS. Long-term use of valproic acid and the prevalence of cancers in bipolar disorder patients in a Taiwanese population: An association analysis using the National Health Insurance Research Database (NHIRD). J Affect Disord. 2018 May;232:103-108. doi: 10.1016/j.jad.2018.02.047. Epub 2018 Feb 19. PMID: 29481993.
  39. Chou CL, Hsieh TC, Chen JS, Fang TC. Risks of all-cause mortality and major kidney events in patients with new-onset primary open-angle glaucoma: a nationwide long-term cohort study in Taiwan. BMJ Open. 2018 Mar 22;8(3):e021270. doi: 10.1136/bmjopen-2017-021270. PMID: 29572399; PMCID: PMC5875628.
  40. Pan MY, Hsieh TC, Tai HC, Lin MS, Lin YC, Chen MY. Prevalence of and factors associated with fewer than 20 remaining teeth in Taiwanese adults with disabilities: a community-based cross-sectional study. BMJ Open. 2017 Oct 8;7(10):e016270. doi: 10.1136/bmjopen-2017-016270. PMID: 28993381; PMCID: PMC5639993.